Histopathology Services for Biopharma Research

Histology and Pathology Services Backed by Human Biospecimen Expertise

ABS Bio delivers comprehensive histology, pathology, and biomarker analysis services that support pharmaceutical, biotechnology, diagnostics, medical device, and academic research programs worldwide.

By combining advanced histopathology capabilities with extensive human biospecimen expertise, we help researchers accelerate biomarker discovery, therapeutic development, translational research, and clinical trial programs.

Integrated Workflows ensure Speed and Quality

Unlike traditional histology laboratories, ABS Bio provides an integrated workflow that spans:

  • Biospecimen Procurement
  • Tissue Processing
  • Pathology Evaluation
  • Biomarker Analysis, and
  • Digital Pathology

This streamlined approach improves specimen consistency, enhances project coordination, and reduces turnaround times.

End-to-End Histology Capabilities

  • Specimen & Processing:
    • Tissue procurement and selection support
    • Gross trimming and tissue processing
    • Paraffin and OCT embedding
    • FFPE and frozen tissue preparation
  • Microtomy & Staining:
    • Cryosectioning and microtomy
    • Routine H&E staining
    • Special stains
    • Tissue microarray (TMA) construction
  • Advanced Analysis:
    • Immunohistochemistry (IHC)
    • Fluorescence in situ hybridization (FISH)
    • Whole-slide digital scanning
    • Quantitative image analysis
    • Board-certified pathology review

Supporting Translational and Preclinical Research

Our experienced histology team supports both human and animal tissue studies, from exploratory research through clinical trial support. We routinely work with challenging specimens, including cell pellets, whole-brain sections, and limited-volume samples, developing customized workflows that meet the scientific objectives of each project.

For decades, our pathology team has supported thousands of specimens and complex research programs with a focus on quality, scientific rigor, and responsive project management.

Custom Tissue Microarrays (TMAs)

ABS Bio designs and manufactures custom tissue microarrays using both client-provided specimens and internally sourced biospecimens. Our team supports project planning, tissue selection, array design, construction, staining, and downstream biomarker analysis.

TMAs provide a cost-effective and scalable solution for biomarker validation, assay development, and translational research initiatives.

Sample Histology Slide Images

Click on any image to view a magnified version.  (Please note that these images are provided for information only, and that viewing resolution may be effected by website software limitations.)

Key Histology & Pathology Terminology

Tissue Processing

Preparing specimens by removing water and infiltrating them with wax for structural support.

Embedding

Placing processed tissues into solid paraffin blocks or liquid OCT compounds for freezing.

Microtomy & Cryosectioning

Cutting tissue blocks into ultra-thin sections using precision blades or a cryostat.

Routine Staining (H&E)

Applying Hematoxylin and Eosin dyes to reveal basic cell and tissue structures.

Special Stains

Using specific chemical dyes to highlight distinct cellular components, fibers, or microorganisms.

Procurement

Sourcing and acquiring ethically collected, clinically annotated human or animal tissues.

Immunohistochemistry (IHC)

Utilizing labeled antibodies to detect, localize, and visualize specific target proteins.

Fluorescence In Situ Hybridization (FISH)

Mapping genetic material by binding fluorescent probes to specific DNA sequences.

Multiplex Immunofluorescence (mIF)

Staining a single tissue section with multiple fluorescent dyes to visualize several biomarkers simultaneously.

Digital Pathology

Scanning physical glass slides into high-resolution digital images for remote review and quantitative analysis.