Advanced Immunostaining Services for Biomarker Discovery & Target Validation

ABS Bio offers a comprehensive portfolio of immunostaining and molecular pathology services designed to reveal protein, RNA, and genomic biomarkers within the context of intact tissue architecture.

Our scientists, histotechnologists, and pathology specialists collaborate closely with clients to develop, optimize, and validate assays that support biomarker discovery, target validation, mechanism-of-action studies, translational research, and companion diagnostic development.

Our immunohistochemistry services provide reliable visualization and quantification of protein expression in human and animal tissues used for biomarker discovery and target validation studies.

• IHC Staining: Standard and custom protocols.
• Assay Development: Custom assay development and optimization.
• Antibody Screening: Cross-reactivity antibody screening.
• Image Analysis: Quantitative IHC image analysis.
• Expert Review: Pathologist interpretation and scoring.
• Clinical Support: Companion diagnostic development and translational biomarker research.

Our team has extensive experience developing custom IHC protocols for difficult tissue types and specialized biomarker applications. We work closely with researchers to optimize antibody selection, antigen retrieval conditions, staining parameters, and scoring methodologies.

Multiplex IF allows simultaneous visualization of multiple biomarkers within a single tissue section, generating deeper biological insights while conserving valuable specimens.

Key applications include:

• Spatial biology studies and immuno-oncology research
• Cell interaction analysis
• Biomarker co-expression profiling
• Precision medicine programs

ABS Bio designs and manufactures custom tissue microarrays using both client-provided specimens and internally sourced biospecimens. Our team supports project planning, tissue selection, array design, construction, staining, and downstream biomarker analysis.

TMAs provide a cost-effective and scalable solution for biomarker validation, assay development, and translational research initiatives.

ABS Bio supports fluorescence in situ hybridization (FISH) and advanced tissue-based molecular analysis workflows for genomic and transcriptomic investigations.

Key applications include:

• Gene amplification analysis
• Chromosomal abnormality, translocation, and fusion detection
• Spatial RNA expression studies