Human Blood & Blood-Derived Biospecimens for Research

Access high-quality blood, plasma, and PBMC specimens from normal and diseased donors, supported by comprehensive clinical annotation and flexible collection programs.

Human Blood Specimens

ABS Bio provides high-quality human blood and blood-derived specimens to support drug discovery, translational research, biomarker development, and clinical assay validation.

Through a global network of clinical collection sites, ABS Bio delivers normal and diseased specimens with rapid turnaround times, customizable collection criteria, and comprehensive patient annotation to support a wide range of research applications.

Capabilities

  • Access normal and diseased blood specimens through remnant and prospective collection programs.
  • Customize collections using study-specific inclusion and exclusion criteria, including age, sex, ethnicity, disease characteristics, smoking status, and other patient factors.
  • Rapid collection and overnight shipping workflows help preserve sample quality and accelerate research timelines.
  • Comprehensive patient annotation may include demographics, medical history, treatment information, laboratory results, molecular testing data, biomarker profiles, and clinical outcomes.
  • Flexible collection protocols support liquid biopsy development, biomarker discovery, translational research, clinical assay validation, and other fit-for-purpose applications.
  • All specimens are collected under IRB-approved protocols with strict quality standards, informed consent, and patient confidentiality protections.

Related Resources

Plasma

ABS Bio provides high-quality human plasma specimens to support biomarker discovery, liquid biopsy development, translational research, and drug development programs. Available through both inventory and prospective collections, plasma specimens are processed to preserve sample integrity and support highly sensitive downstream analytical applications.

Key Features

  • Access normal and diseased plasma specimens through inventory and prospective collection programs.
  • Double-spun plasma processing minimizes residual cellular contamination for high-sensitivity applications, including cfDNA, ctDNA, extracellular vesicle, RNA, and miRNA analysis.
  • Available in a variety of collection formats and volumes to support biomarker discovery, liquid biopsy development, pharmacokinetic (PK), and pharmacodynamic (PD) studies.
  • Comprehensive patient annotation may include demographics, medical history, treatment information, laboratory results, molecular testing data, biomarker profiles, and clinical outcomes.
  • Rapid collection and processing workflows help preserve sample integrity and support advanced molecular and analytical assays.
  • All specimens are collected under IRB-approved protocols with strict quality standards, informed consent, and patient confidentiality protections.

Serum

ABS Bio provides high-quality human serum specimens to support immunology, biomarker discovery, assay development, cell culture, and translational research. Available through both inventory and prospective collection programs, ABS Bio offers normal and diseased serum samples processed to deliver consistent quality, reliable performance, and comprehensive patient annotation across a broad range of downstream research applications.

Key Features

  • Access normal and diseased serum specimens through a worldwide network of clinical collection sites, with both inventory and prospective collection options available.
  • Widely used for antibody detection, serology, vaccine research, autoimmune disease profiling, and immunological assay development.
  • Supports biomarker discovery, diagnostic development, cell culture applications, and translational research across a broad range of therapeutic areas.
  • Comprehensive patient annotation may include demographics, medical history, treatment information, laboratory results, molecular testing data, biomarker profiles, and clinical outcomes.
  • Rapid collection and processing workflows help maintain sample quality and consistency across research programs and assay platforms.
  • All specimens are collected under IRB-approved protocols with strict quality standards, informed consent, and patient confidentiality protections.
human serum

PBMCs

ABS Bio provides high-quality human PBMCs (Peripheral Blood Mononuclear Cells) to support immunology research, cell and gene therapy development, biomarker discovery, and translational research. Available from normal and diseased donors, PBMCs are delivered with high viability, comprehensive patient annotation, and flexible collection options to support a broad range of research and therapeutic development programs.

PBMCs are widely used in immuno-oncology, autoimmune disease research, infectious disease studies, and advanced cell-based assays.

Applications and Capabilities

  • Access normal and diseased PBMCs through inventory and prospective collection programs.
  • Supports immuno-oncology research, cell and gene therapy development, immune monitoring, biomarker discovery, infectious disease research, and autoimmune disease studies.
  • High-viability PBMCs support flow cytometry, functional immune assays, cell culture, cytokine profiling, and molecular analysis.
  • Comprehensive patient annotation includes demographics, medical history, treatment information, laboratory results, molecular testing data, biomarker profiles, and clinical outcomes.
  • Custom collection and processing protocols can be tailored to study-specific inclusion and exclusion criteria, disease-specific requirements, and translational research objectives.
  • All specimens are collected under IRB-approved protocols with strict quality standards, informed consent, and patient confidentiality protections.

Blood & Blood-Derived Biospecimen Glossary

Whole Blood Samples

Whole blood samples are blood specimens collected directly from a donor and preserved without separating their cellular and liquid components. Whole blood contains red blood cells, white blood cells, platelets, and plasma, making it useful for hematology, molecular biology, biomarker, and diagnostic research applications.

Human Plasma Samples

Human plasma samples are obtained by collecting blood into anticoagulant-treated tubes and separating the liquid portion from blood cells through centrifugation. Plasma contains water, proteins, hormones, electrolytes, and clotting factors and is widely used in biomarker discovery, proteomics, pharmacokinetic studies, and clinical research.

Human Serum Samples

Human serum samples are produced by allowing blood to clot before separating the liquid component. Unlike plasma, serum does not contain clotting factors such as fibrinogen. Serum is commonly used in diagnostic testing, immunology research, biomarker analysis, and assay development.

PBMC Samples

Peripheral Blood Mononuclear Cell (PBMC) samples consist of immune cells isolated from whole blood, including lymphocytes (T cells, B cells, and NK cells) and monocytes. PBMCs are widely used in immunology, oncology, infectious disease, cell therapy, vaccine development, and functional immune response studies.

Buffy Coat Samples

Buffy coat samples are concentrated fractions of white blood cells and platelets that form between the plasma and red blood cell layers after blood centrifugation. Buffy coat specimens are frequently used for DNA extraction, genomic research, biomarker studies, and applications requiring enriched nucleated cell populations.

Peripheral Blood Mononuclear Cells (PBMCs)

Peripheral Blood Mononuclear Cells (PBMCs) are a subset of blood cells characterized by a single round nucleus, including lymphocytes and monocytes. PBMCs play a central role in immune system research and are commonly isolated for cell-based assays, flow cytometry, immune monitoring, and therapeutic development.

Anticoagulant

An anticoagulant is a substance added to blood collection tubes to prevent clotting during sample collection and processing. Common anticoagulants include EDTA, heparin, and sodium citrate, each selected based on the intended downstream research application.

Fresh Blood Samples

Fresh blood samples are specimens processed and delivered shortly after collection to preserve cellular viability and biological integrity. These samples are often required for functional assays, cell isolation, flow cytometry, and other time-sensitive research applications.

Cryopreserved PBMCs

Cryopreserved PBMCs are isolated peripheral blood mononuclear cells that have been frozen under controlled conditions for long-term storage. Cryopreservation allows researchers to maintain viable immune cell populations for future analysis while reducing variability across studies.

Prospective Blood Collection

Prospective blood collection is the customized collection of blood specimens from donors according to study-specific inclusion criteria, collection protocols, processing requirements, and clinical data needs. Prospective collections enable researchers to obtain specimens that meet precise project requirements when existing inventory is unavailable.

Biospecimen Annotation

Biospecimen annotation refers to the clinical, demographic, pathological, or laboratory information associated with a biological sample. Depending on study requirements and donor consent, blood biospecimens may be accompanied by anonymized clinical data that enhances research value and supports more meaningful analysis.

Disease-State Donors

Disease-state donors are individuals with a diagnosed medical condition whose biospecimens are collected to support disease-specific research. Blood samples from disease-state donors are commonly used in oncology, autoimmune, infectious disease, neurological, and rare disease studies.

Healthy Control Samples

Healthy control samples are biospecimens collected from individuals without the disease or condition under investigation. These samples provide an important baseline for comparison and help researchers distinguish disease-related biological changes from normal variation